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fresh frozen tumor tissue  (Qiagen)


Bioz Manufacturer Symbol Qiagen manufactures this product  
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    Qiagen fresh frozen tumor tissue
    Fresh Frozen Tumor Tissue, supplied by Qiagen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fresh frozen tumor tissue/product/Qiagen
    Average 90 stars, based on 1 article reviews
    fresh frozen tumor tissue - by Bioz Stars, 2026-02
    90/100 stars

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    Promising DNA methylation markers predictive of resistance to platinum-based chemotherapy (studies with patient samples). Genes related with the three most common platinum drug resistance pathways are indicated as [T], genes encoding proteins’ transporters, related with cellular uptake of platinum drugs; [R], genes encoding proteins responsible for DNA damage repair; or [A], genes encoding proteins related with induction of apoptotic cell death.

    Journal: Cancers

    Article Title: DNA Methylation Biomarkers for Prediction of Response to Platinum-Based Chemotherapy: Where Do We Stand?

    doi: 10.3390/cancers14122918

    Figure Lengend Snippet: Promising DNA methylation markers predictive of resistance to platinum-based chemotherapy (studies with patient samples). Genes related with the three most common platinum drug resistance pathways are indicated as [T], genes encoding proteins’ transporters, related with cellular uptake of platinum drugs; [R], genes encoding proteins responsible for DNA damage repair; or [A], genes encoding proteins related with induction of apoptotic cell death.

    Article Snippet: PAX9 , CDDP , OC , Fresh frozen and FFPE tumor tissue samples , 189 patient samples (129 FFPE and 57 frozen samples) , n.m. , Bisulfite sequencing; MSP; qMSP; whole-genome bisulfite sequencing; Infinium ® HumanMethylation450K BeadChip , Kaplan–Meier analysis showed that resistant/ PAX9 -methylated patients had reduced OS compared to cases without methylation. Moreover, patients with low PAX9 expression disclosed shorter OS and recurrent disease. , [ ] .

    Techniques: DNA Methylation Assay, Methylation, Expressing, Combined Bisulfite Restriction Analysis Assay, Methylation Sequencing, Biomarker Discovery, EpiTYPER Assay, Gene Expression, DNA Sequencing, Control, Phospho-proteomics, Activation Assay, Derivative Assay, Mass Spectrometry